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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f90c0f7e7b5c371be5dec280dae500ff58d7ab1d33b9b06b15102aebd0549ad8' 
  AND token = 'M2+lq+7443hgiAtMpT9Xcfwn6nT/TS6gjhL4jSNB7dU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}