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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1222813c0b9033c3fe7048c6389dc25874024cb046d9ace59ae20688bc6b9d4e' 
  AND token = 'mMmC0YDEpCVfZheCQYFN6mBkYwKqv93U8nZeaNZXtD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}