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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff289132d712dd7a640c7ccc887b0fb3667f8438c03cd4d211bee25afa50dfc0' 
  AND token = 'qxB1BBSdd+mnUmY3omR7jxZ7Ox6BBDLFoeZUPaFX5K4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}