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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af606ea1166a488c30d75595697315905e07f50a8925173d93d288518ff8e139' 
  AND token = 'U3zd0R6RLAJPSnp++55njiScwx7y7vnWHstX4WApQeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}