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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fe415f14d0e2cb75fa592ab242bee11b2c99de8791e590d7d8cda31dedb352c' 
  AND token = 'Pf6vq9cXsHqP7TTZrVmjDfcevy6ZXLhNHtT3vH+PJIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}