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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f8f5c8934d2c54b40698a6d3c9ac190ec11229d3a6914815c44c8c31153f45' 
  AND token = 'wvd5Rjg8ZZgftic3SUuZ9qndpj4nz+xqXrLyNUxVS/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}