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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74d5de4e655f08855717c4658127f35eb34d03e0d7679149efc9a09468791f69' 
  AND token = 'bPUNrXTSmz2Gqai8IpyYgkg2G1Z0jb9HvYjG9ZcHFXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}