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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b03e9db6fba596743c469f25926c2cf3f05ad15892b60646127a7f6980a05fc' 
  AND token = 'fj/G6iX4pD1Y0k2YQWLutHK9FyjTZ6+pZxeIqZgdKSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}