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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4af69b66f2f6f3cd8a5868c1291d384957df01e6a7f42322cff36a1c4386bc52' 
  AND token = 'aUP9RywGjaMJHxEu3s5igAj8aeqLmteYycN37EAZm4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}