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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7781a66ef15f8b983e13453eb9f69254fa6765681189f2a9b41a9ce97c127b06' 
  AND token = 'XtVVeJMSlOxPEaiHWHNRsvRtcOkpx68H/V71FqhNks0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}