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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc3e076c61f8da325364636d06b65ad4b42eaad3756a921fefd062688d24856b' 
  AND token = 'x+cJrFKzDY1+uc1degQdQvMYvVaxixiF0FBO3r/v/xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}