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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f43304bfd423f47e533d7af3a59978f03abde8a192e12aec59b13e4e7ede9fec' 
  AND token = 'abYCjE2A2YuhjLQPnsB2BTyPw2xOYuH2xUpYv8zT9EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}