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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '361d57b27904461f7736ef5ec071646a936d5b0e6ea34be02fb52276b18d43ad' 
  AND token = 'RE31PKl3s2NQXohDI1Cj0mveKMnDWp97mVT+FI0TltM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}