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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e549f6a8c98cb823adc2ca48f07e16c7c923bcdc753b1ac96d7541b04f7d8c7c' 
  AND token = 'jXUbefgHFM6pePCJbE0noPB49AMeaibh4xteFDWxvSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}