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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49347862ee998ee99147527c9904c26ca27193b0e681528b94166702e7f6e8ef' 
  AND token = '31FmmqQD5cfg1uaF5K3nDAKWi47C1VG+kfNrPlnCXc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}