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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3abeeb4536e2cf70af1e1ddbbe822c9334e589ba5344a34b4bd6e46532d1da8f' 
  AND token = 'oN0C8OUy8I7oSxzVjiTKM2zmtvMzRfnQaD4N2XTW8UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}