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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89e6fe56b62858f4cd2c636c416ceb29501bcb6ee38a5df3b40b90163f464994' 
  AND token = 'Ev1bZ3201UtrJdcqA2K3PeJc3yIeOtEpwpkWYnr76G0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}