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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e7a91e8f90ac5729937fc16b12321d469f94b81ea6cb6fad442883d8c412365' 
  AND token = 'PDg2xf7COicgcoDSGJ3IJ6zNKoj9AyBH5x9i5yV5iDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}