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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c038bb4b61c55fa1b7bf95bcd362bdfa20a565d689f2ecc7f94c91d518b9b80' 
  AND token = 'EHHi0W5IWq6pmkgzeg+NoJMdZgrOvbBMqhx+NpI/62k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}