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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f78c6d6c849b6de6442a26eda1438b0bafa2aba769dca3302f45bb8db54a8f55' 
  AND token = 'Ba2F3zbWo45/mjw/eQJx7q+JRzATDQRLpNQu6VO7L6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}