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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8adfac4e1a423ab1231dc43bf094253554a5fe2897c0ca9249ecf72bcbc595b5' 
  AND token = '+yIF/zmR7DhsM90Nib2YzizmkPyaU4dCVtE7xkYUkYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}