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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bee94ee289ebab85833a4f4bc379f1364eb7f1cf0f2f824120676aad46c1c6ad' 
  AND token = 's480cfw5TwNeKV95yA9bhtIA/0czFzAsK/JMgNQJem4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}