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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bccc36151a87246a6c1312e0c45ff169bf69d0b0bfad0592ef2807d1138df05' 
  AND token = 'Ld43eJ0Wsmks/I3DNGTV9T6XCaa2qQjRhyAyaMBDtPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}