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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0acf8920eff700a1d76719f3a836d1724e0c7edd5099753257850253143462f2' 
  AND token = '8DfVl0H/pFAUrtFrwq7Qm9gRZGmc21BsXZ5ZRymkKag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}