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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '408f91af2961650e86a7315429a997c8c6f77ce17325bdd71c7d8c670209ba68' 
  AND token = 'qZhYKFlVlTMDr/5P6aNL1+jne2RoHN8y6OvivNZvHyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}