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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c2660525374cd34997660fdf535fafc717460911c55305913dd4c830da5731f' 
  AND token = 'JkQCxbAqm0nyiGqNicT+2AghusNT3rY0V9hPWvURWZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}