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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0257ebcb1bca9342a07dd6969307f34531d1c8e908bf5670df2052fe70eff733' 
  AND token = 'sHm5wHFzKz5QOThVqp6Va2+0eyWe7Fr0mT68L0lOJs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}