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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb9987cfb1d6dcbe2db3499738d40b5299ce8467db319bb972c60ce44a030e0b' 
  AND token = 'KxBZd1nIoAg6p0AL0yVUmeYLRBLVd3YggPQI2KKyFPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}