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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '742fe948ee96bfd4f3ed2739e6d25b167ecf4521a44182e2d35b5141c7b22437' 
  AND token = '4gnICyhx2cqUsXmFjEH8Nb/GixQOUHffve7NctfZRvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}