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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff0771385ba36a815f26dcf9d1edc964e83a73c5363012682580a50be5e086b3' 
  AND token = 'RRMdiAqwRF1ySlv47/awsvaC2SehMRFRcou2GPCmSEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}