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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a0dcf50fcffe6388eeea8d048f87033cb13d6dbad84514f94e7746c489aa646' 
  AND token = 'M40qReWYPR/hquneoUx5uiJ5o2HgKB1C2ky9W5VdsWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}