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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b0cae9bd7d59cff884f33d4736bd8ec39b124c01d871d252c9ed1df813f1142' 
  AND token = 'syXp7fXOhAT5idy+ok08gSDE5P8sl6qwpfzxrbNt6kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}