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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20c152a347bc73abe2b59ff33f2acea8db4868faa02133105da42c4bbb172b89' 
  AND token = 'zrrPVqmSKvsH/2zSXwLBiUtuH0vCHiSr2W55qCy+S/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}