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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9acd797eedd8d256352904da8c7e1718c31f781f15230378bf2f2c3812650740' 
  AND token = '5ojN7fkGcsgOz2m4/rjSi3dL2k2PXfpBk/gv0F3880o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}