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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163bc7513ba47895bf7a57ba6978b373db78ff2bff748e6f21b3ca45b236a606' 
  AND token = 'aQX395upZmE2u8g51MxQPChZxOd30NUI0EavpLCjbBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}