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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09e3c9840a009c0526f81f355de15be32dbb86932ddd325c8ba915f17620c060' 
  AND token = 'ATCR2+PQCypGYxtyzbgye523VK6gdEQlwjeMPqtTDWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}