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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dc90fc425daf7b53d4e19abb44116962ef8c220b4777cc853f9bf31582b2976' 
  AND token = 'i1zEFxW9ZPnTGadw2Trxpo0yZkFziU+Ykzz+9qL/Dss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}