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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06b78c64c7401ffa8aac3d91970a868f318fbb4a3838bd8dbae29ed3e78fb3aa' 
  AND token = '+78t+XxR7lTH+HOWJsxH/6O2T+NU1kcTnCkFX3vokfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}