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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6153ba53413f0be615f793f2599d54b925af1e66c2573debea0570033e9ab8d0' 
  AND token = '2iADP7GSe7ldp+tFpVudhe1xFDNZs/wyp2yi+E8ZdSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}