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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8924ecd567b37b66148ea040ee92a992a5eff541efb5159f6d8a5fbf1bfabda' 
  AND token = '8anu7S/v4MMmoJTKDmEXEy/pfzwIQt3DvLRg3Ly1O/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}