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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76c580306286bc4dca30c54c6d42ed01b1c84422c2961f038b56f946c46e0574' 
  AND token = 'fGVTX/Ir4KT/kMDl+chB/uWq+SoU7wmKb7/x8UOBeh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}