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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729b03fac88d46b7368061b16c2db35c0e99764d1a02f6de823d8280bd812bd1' 
  AND token = 'bw4iXCwCDIWoJujNsBBCw5sDUIqghKFcB5higCKcbpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}