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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a55b96a850063a4d017a681c0e5e1073f12e78a7f4dfabdb64c41c9e60b3db' 
  AND token = '34QiqNn152TsS9vnsfqFqArcjWmltiu+GfcKndvt/v4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}