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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfd929e43406025576b018016d221480d4722ec0ee1b63b009ab8db6d44cadc5' 
  AND token = 'd//b3AcmPBx9IId72jR1tKNF+hQLmBqQKXsg/0N2ZgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}