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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88901bf2bcd3afe5a47369b54f1310bdb8e25fb55df14d40fac293840a51d150' 
  AND token = 'zQsxlXSxjjdwMtJaiyCKHZ+u+OEC1Xdu2ejSaZME/kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}