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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e00d6c0a8de9f3be170d4bfeee1484c10bdbda107966fd6b42e9c521c0264b9' 
  AND token = 'EV4rrF7N0/5LqzwlH8lHyQgQU+GellYKKi1kw7IjMBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}