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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2443a3e86d72e6cbc6e715db84286ca51d15670c344bcf1406ff101791b86257' 
  AND token = '5g0I48Bo07LVXCC2h1EprgQAPOpmz4z7kZZIYC9vRcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}