SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cacbf13c5307fd39beeca04c93b685ec1f4cabc3c4609215cdae60239163b35c' 
  AND token = 'BUP5bBzsHnjum9yqcfTH5HspIjuSayiAMURkOP5cmmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}