SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '970c7b973526b8799ad1bd1802ffebbe0d6df629cfb4bd639474c6169f9f4880' 
  AND token = 'VXrAGm3QT+mWAgjjHie49HLLoDnTm8N/WaxT19uokqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}